What Is Lamin A Protein And Why Is It Important

The small difference in the sequence makes lamin a longer than lamin c.

What is lamin a protein and why is it important.

Protein is an important building block of bones muscles cartilage skin and blood. Lamin a plays an important role in nuclear structure and function and mutations in the lamin a gene cause a large number of different human diseases including cardiomyopathies muscular dystrophies and hutchinson gilford progeria syndrome broers et al 2006. Here are five compelling reasons why you should make sure you are getting enough protein every day. Your body uses it to build and repair tissue.

Parnaik and manju 2006. The word protein comes from greek language meaning of primary importance. Laminins are high molecular weight 400 to 900 kda proteins of the extracellular matrix they are a major component of the basal lamina one of the layers of the basement membrane a protein network foundation for most cells and organs the laminins are an important and biologically active part of the basal lamina influencing cell differentiation migration and adhesion. Why your body needs protein.

Lamin proteins are involved in the disassembling and reforming of the nuclear envelope during mitosis the positioning of nuclear pores and programmed cell death. Verstraeten et al 2007. It s time to learn why protein is important and how it helps maintain a healthy weight and keep your body functioning properly. Protein is an important building block of bones muscles cartilage and skin.

Mattout et al 2006. Along with fat and carbohydrates protein is a macronutrient meaning that the body needs relatively large. The lamins are the major architectural proteins of the animal cell nucleus. These proteins are made up of a nearly identical sequence of protein building blocks amino acids.

They have been implicated in a wide range of nuclear functions including higher order genome organization chromatin regulation transcription dna replication and. Members of the groel hsp60 protein family have been studied for many years because of their critical roles as atp dependent molecular chaperones so it might come as a surprise that some have important functions in atp poor conditions for example when secreted outside the cell. At least some membe. Laminin an important protein that looks like a cross truth.

The two major proteins produced from this gene lamin a and lamin c are made in most of the body s cells. In fact your hair and nails are comprised mostly of protein. Mutations in lamin genes can result in several genetic laminopathies which may be life threatening. Lamins line the inside of the nuclear membrane where they provide a platform for the binding of proteins and chromatin and confer mechanical stability.